This article explains how Compounded Liraglutide with B12 compares to semaglutide, how to inject Compounded Liraglutide with B12, how the liraglutide dose titration schedule works, and what to do if you miss a dose. Use this article if you are starting Compounded Liraglutide with B12, switching from semaglutide, or need help understanding your daily injection schedule.
How does Compounded Liraglutide with B12 compare to semaglutide?
Compounded Liraglutide with B12 is a daily injection. Semaglutide is a weekly injection.
Both liraglutide and semaglutide are GLP-1 receptor agonists. GLP-1 receptor agonists were originally developed for the treatment of type 2 diabetes and are now widely used for weight management.
In a 68-week study, semaglutide 2.4 mg weekly led to a mean weight loss of approximately 15% of total body weight.[1]
In a 56-week study, liraglutide 3.0 mg daily led to a mean weight loss of approximately 8% of total body weight.[2]
For safety and optimal results, both semaglutide and Compounded Liraglutide with B12 should be taken under medical supervision and alongside lifestyle changes, including increased physical activity and a reduced-calorie diet.
References
[1] Wilding JPH et al.; STEP 1 Study Group. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine. 2021 Mar 18;384(11):989–1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10.
[2] Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine. 2015 Jul 2;373(1):11–22. Available from: https://www.nejm.org/doi/full/10.1056/NEJMoa1411892
Is the Compounded Liraglutide with B12 injection process the same?
Compounded Liraglutide with B12 is administered by subcutaneous injection once daily. A subcutaneous injection means the medication is injected just under the skin using a disposable needle.
Follow these steps to administer your Compounded Liraglutide with B12 injection:
Wash your hands.
Gather your medication vial, alcohol swab, disposable needle, and sharps bin on a clean surface.
Check your medication for signs of damage or expiration.
Choose an injection site, such as your abdomen, thigh, or upper arm.
Clean the injection site with an alcohol swab.
Choose a new injection site each time you inject Compounded Liraglutide with B12 to help prevent skin irritation at the injection site.
Remove the needle cap.
Draw up the prescribed Compounded Liraglutide with B12 dose into the syringe.
Remove any air bubbles by gently tapping the syringe.
Insert the needle into your injection site at a 90-degree angle.
Slowly push the plunger down while counting to 5.
Dispose of the needle in a rigid plastic sharps container.
Will I need to titrate the dose up again with Compounded Liraglutide with B12, like I did with semaglutide?
Yes. Compounded Liraglutide with B12 has a recommended weekly titration schedule.
Follow the Compounded Liraglutide with B12 dose schedule provided by your clinician:
Treatment week | Daily dose | Volume | Syringe units | Frequency |
Week 1 | 0.6 mg | 0.2 mL | 20 units | Once daily |
Week 2 | 1.2 mg | 0.4 mL | 40 units | Once daily |
Week 3 | 1.8 mg | 0.6 mL | 60 units | Once daily |
Week 4 | 2.8 mg | 0.8 mL | 80 units | Once daily |
Week 5 onward | 3 mg | 1 mL | 100 units | Once daily maintenance dose |
What do I do if I miss a dose of Compounded Liraglutide with B12, and how does a missed dose affect titration?
If you miss a dose of Compounded Liraglutide with B12, take the missed dose as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed dose and take your next dose at the regular scheduled time.
Do not take double doses or extra doses of Compounded Liraglutide with B12.
If you miss your Compounded Liraglutide with B12 injection for more than 3 days, you may need to reduce your dose back to your starting amount.
If you have questions about what to do after missing a dose of Compounded Liraglutide with B12, contact the Levity clinical team for advice. You can also call Levity at (855) 644-0928. Lines are open Monday to Friday, 9am–5pm EST, or you can leave a message here.
*Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA review for safety, effectiveness, or quality
If you still need help after reviewing the information above, additional assistance is available.